dissoBOT®
Automated dissolution system
dissoBOT®
The world's first fully automated dissolution system with clip-on/off capability.
Advanced dissolution automation is built around world’s leading dissolution system – Agilent 708-DS Dissolution Apparatus and Agilent 850-DS Dissolution Sampling Station and optional filtration module.
Working principle
Latest technology in collaborative robotics
Advanced automation is performed with the help of the latest technology in collaborative robotics. The clip-on/off capability enables users to extend their working cycles on existing dissolution systems. There is no interference in the dissolution process and the clip-on procedure takes less than a minute. DissoBOT® system takes over the control of the dissolution apparatus and sampling station.
Working principle
Fully automated cycles
Advanced dissolution automation technology of dissoBOT® performs fully automated sequential cycles of cleaning, media dispensing, and introduction of new dosage forms to the dissolution apparatus.
The dissolution process
Automatically activated dissolution process.
When dissoBOT® takes care of cleaning, media dispensing and dosage forms introduction, it is time for a dissolution process. The Dosage Delivery Module (DDM) is activated automatically. The dissolution itself is performed with standard 708-DS Dissolution Apparatus featuring a smooth-operating, motorized lift for reproducibility and integration with automated systems. Sampling is performed with an automated sampling manifold using the 850- DS Dissolution Sampling Station and optional filtration module. The system collects samples into test tubes, HPLC vials or well plates for subsequent analysis. Temperature is monitored with precise in-vessel monitoring AutoTemp. The individual vessel values may be documented initially, at each pre-programmed time point, and after the test has concluded.
Highlights
System Functionality
Overview
- Clip-on/off platform with table-top collaborative robot
- Sequential cleaning, media dispensing and samples introduction
- Standard Agilent 708-DS Dissolution Apparatus and 850-DS Dissolution Sampling Station
- Suitable for Apparatus 2 (paddles) and Apparatus 1 (baskets)
- Internal tanks and external connections
Technical information
Specifications
dissoBOT®
Advanced Dissolution
Automation Module
708-DS
Dissolution apparatus
850-DS
Dissolution Sampling Station
Brochure
Want to know more?
Integration of dissoDG in dissoBOT
Integrated within the dissoBOT system, efficient dissoDG removes dissolved gases according to USP requirements for media degassing. Media in dissoDG is degassed on demand and dispensed precisely straight into the dissolution vessels.
Large Tubing Kit
A custom tubing kit featuring tubing of wider inner and outer diameter for increased flow and improved viscous media handling with Agilent 850-DS autosampler. Kit includes cannulas, connection tubing, fittings and inner tubing connection in the 850-DS.
Robot Vial Rack Holder
A secure and effective solution for holding vial racks, designed to transport vial racks from Agilent 850-DS autosampler to HPLC Multisampler or any other instrument compatible with IDIS software.
dissoSHIELD for dissoBOT
Ambient protection of your sensitive samples now made available also to work with our full dissolution automation system dissoBOT.
dissoBOT®
